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To promote the health and safety of our university community, UC currently has a mandatory mask requirement for all buildings on campus for faculty, staff, students, and visitors. Additionally, successful applicants for this position must be fully vaccinated against COVID-19 as a condition of employment. Vaccine verification will be required by November 15, 2021. Newly hired individuals will be required to provide proof of their COVID-19 vaccination. There is an opportunity to request an exemption from the vaccine requirement for medical reasons, sincerely held reasons of conscience, or religious beliefs.

Research Associate, Facility Manager for Cryogenic Electron Microscopy

Current UC employees must apply internally via SuccessFactors > http://bit.ly/UCEMPL


Founded in 1819, the University of Cincinnati embarks upon its third century – building on the past and defining the future by leading urban, public universities into a new era of innovation and impact through its strategic direction, Next Lives Here. Underscoring the power of creativity, ingenuity, invention and inclusion, what’s Next will accelerate our unrivaled momentum, evidenced by eight straight years of record enrollment and rankings that include placement among America’s top 100 public universities by U.S. News & World Report. Home to a diverse student body of nearly 47,000 and more than 4,200 distinguished faculty, the university combines its Research 1 (Very High Research Activity) Carnegie Classification with a physical setting that The New York Times recently acclaimed as “the most ambitious campus design program in the country.


Job Overview

As one of the oldest medical schools in the country, the UC College of Medicine has a reputation for training best-in-class health care professionals and developing cutting-edge procedures and research that improves the health and clinical care of patients.
The College of Medicine at the University of Cincinnati is seeking applications from outstanding individuals to fill the Facility manager position in the newly established Center for Advanced Structural Biology.  Core facilities at UC are centralized shared research resources that provide access to instruments, technologies, training and services as well as expert consultation to scientific and clinical investigators within the Tri-state scientific community.  The facility manager will report jointly to the College of Medicine Associate Dean for Research Core Facilities and to the Chair of the Department of Molecular Genetics, Biochemistry, and Microbiology.  Responsibilities will include overseeing all operations associated with running a state-of-the-art cryogenic-Electron Microscopy (cryo-EM) facility that will include a Talos L120C and 200 kV Glacios cryo-TEM microscope equipped with a Falcon 4D direct detector, Mark IV vitrobot system and other related equipment. Applications should include a cover letter highlighting relevant expertise, a CV with publication list, and contact information for three references.

Essential Functions

  • Maintain and operate a Talos L120C, Glacios cryo-EM with Falcon 4D detector, Mark IV vitrobot system and accompany equipment. 
  • Prepare instructional guides for use, calibrating, maintaining and repair of core instruments. 
  • Keep detailed records on instrument use, service, and operational specifications. 
  • Maintain core billing and finance via Stratocore system in conjunction with the designated financial group. 
  • Perform monthly performance and calibration test, daily alignment checks, troubleshooting equipment performance issues, manage service contracts and coordinate external servicing with vendor engineers. 
  • Assist in the selection, procurement, installation and design of future cryo-EM and electron tomography instrumentation. 
  • Train research staff and students in instrument operation and implementation of high-through put workflow for data collection and analysis. 
  • Serve as the facility expert for all instrumentation used in core and facilitate regional researchers in all aspects of data acquisition and analysis in single particle cryo-EM and electron tomography.  
  • Ability to work independently and as part of a larger team. 
  • Perform related duties based on departmental need. This job description can be changed at any time.

Required Education

Bachelor’s Degree in cell biology, structural biology, or a related field.

Required Experience

  • 3 years of experience working with and maintaining high-end electron microscopes and automated systems. 
  • Experience in computational programing and automated data collection software.

Additional Qualifications Considered

  • Master’s Degree in cell biology, structural biology, or a related field.
  • Experience in analyzing biological samples with single particle cryo-EM or cryo-electron tomography. 
  • Experience with training research staff in all aspects of EM.
  • Effective interpersonal skills demonstrated through past experience.


The University of Cincinnati, as a multi-national and culturally diverse university, is committed to providing an inclusive, equitable and diverse place of learning and employment. As part of a complete job application you will be asked to include a Contribution to Diversity and Inclusion statement.


As a UC employee, and an employee of an Ohio public institution, if hired you will not contribute to the federal Social Security system, other than contributions to Medicare. Instead, UC employees have the option to contribute to a state retirement plan (OPERS, STRS) or an alternative retirement plan (ARP).


The University of Cincinnati is an Affirmative Action / Equal Opportunity Employer / Minority / Female / Disability / Veteran.


REQ: 68922 


Research Associate, Facility Manager for Cryogenic Electron Microscopy

Date:  Sep 11, 2021

Cincinnati, OH, US

Facility:  Main Campus

Nearest Major Market: Cincinnati

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