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Research Associate, Biochemistry Division, Chemistry, Grillo Lab

Current UC employees must apply internally via SuccessFactors >


Founded in 1819, the University of Cincinnati ranks among the nation’s best urban public research universities. Home to more than 47,000 students, 10,500 faculty and staff and 330,000 alumni, UC combines a Top 35 research university with a physical setting The New York Times calls “the most ambitious campus design program in the country.”


With the launch of Next Lives Here, the Cincinnati Innovation District, a $100 million JobsOhio investment, eight straight years of record enrollment, worldwide leadership in cooperative education, a dynamic academic health center and entry into the Big 12 athletic conference, UC’s momentum has never been stronger. UC’s annual budget tops $1.6 billion and its endowment totals $1.9 billion.


Job Overview

The Grillo Lab ( is seeking post-baccalaureate candidates to join our vibrant team in a full-time position as a Research Associate. Research in the Grillo Lab focuses on the molecular understanding of how genetic, age-related, or environmental-induced mitochondrial dysfunction alters metabolism through molecular oxygen pathogenicity and metal-mediated proteostatic failure in neurologic disease. Our research at the interface of biochemistry, metabolic physiology, and medicine employs multiple in vitro and in vivo models to investigate the basic biochemistry and molecular mechanisms of inborn errors of metabolism and age progressive neurodegenerative diseases.


The Research Associate will perform laboratory experiments on an independent project under the supervision of Dr. Grillo while assisting other laboratory personnel including postdoctoral scientists, graduate students, and undergraduate students. The primary goal of the research project is to investigate the molecular mechanisms by which mitochondria influence tau aggregation in cells and mice. These experiments may include, but are not limited to, techniques such as PCR, qRT-PCR, RNA isolation, western blot, ELISA, immunoprecipitation, ICP-MS, flow cytometry, etc.; tissue collection, fixation, sectioning, immunostaining, and imaging; quantification of oxidative stress markers; isolation and cell culture of primary neurons or cell lines; and other experiments as deemed necessary. This position may also include management of our mouse colony such as genotyping, weaning, treating, etc.


This position is for a one-year appointment with the opportunity for renewal upon satisfactory progress.

Essential Functions

  • Independently perform research experiments on an independent project and properly record data according to research protocols under the mentorship of Dr. Grillo.
  • Troubleshoot experimental protocols, organize complex data, and analyze/interpret results within the context of the overarching research project.
  • Read, analyze, evaluate, and critique primary research related to the project.
  • Assist in establishing test controls, criteria, and research standards.
  • Accomplish assigned aspects of larger research projects as needed.
  • Actively help and/or train other laboratory personnel including postdoctoral scientists, graduate students, and undergraduate students based on professional training or functional experience.
  • Effectively communicate experimental hypotheses, protocols, analyses, results, and project details in one-on-one or group meetings, journal clubs, conferences, etc.
  • May maintain and oversee animal colony management and animal husbandry.
  • Assist in the preparation of research papers, grants, and other documents.
  • Demonstrate continual success in performing increasingly complex experiments or projects that require improved technical skills.
  • Perform related duties based on laboratory needs. This job description may change as the research project progresses.

Required Education

Bachelor's Degree in biochemistry, molecular biology, chemistry, physiology, cell biology, or a health-related discipline at the time of appointment.

Required Experience

  • In-depth knowledge of specialized field, process or discipline.
  • May require experience with specialized software programs. 

Additional Qualificatins Considered

  • At least 2 years of experience in a laboratory environment performing basic research.
  • Knowledge of metabolism and/or metals in age-related disease.
  • Experience in techniques such as western blot, RT-PCR, ICP-MS, etc.
  • Experience working with animal disease models (e.g. mice, worms).
  • Experience with cell culture, isolating primary neurons, and aseptic technique.
  • Ability to communicate effectively and respectfully, an attention to detail, and willingness to learn while working closely with others.

Physical Requirements/Work Environment

  • Sitting - Continuously

Application Process

Applicants must upload the following documents:

  • Cover Letter
  • CV/Resume
  • Contact information for up to three (3) recommenders.


Compensation and Benefits

UC offers a wide array of complementary and affordable benefit options, to meet the financial, educational, health, and wellness needs of you and your family. Eligibility varies by position and FTE.

  • Competitive salary range dependent on the candidate's experience.
  • Comprehensive insurance plans including medical, dental, vision, and prescription coverage.
  • Flexible spending accounts and an award-winning employee wellness program, plus an employee assistance program.
  • Financial security via our life and long-term disability insurance, accident and illness insurance, and retirement savings plans.
  • Generous paid time off work options including vacation, sick leave, annual holidays, and winter season days in addition to paid parental leave.
  • Tuition remission is available for employees and their eligible dependents.
  • Enjoy discounts for on and off-campus activities and services.


The University of Cincinnati, as a multi-national and culturally diverse university, is committed to providing an inclusive, equitable and diverse place of learning and employment. As part of a complete job application you will be asked to include a Contribution to Diversity and Inclusion statement.


As a UC employee, and an employee of an Ohio public institution, if hired you will not contribute to the federal Social Security system, other than contributions to Medicare. Instead, UC employees have the option to contribute to a state retirement plan (OPERS, STRS) or an alternative retirement plan (ARP).


The University of Cincinnati is an Affirmative Action / Equal Opportunity Employer / Minority / Female / Disability / Veteran.


REQ: 88099 


Research Associate, Biochemistry Division, Chemistry, Grillo Lab

Date:  Dec 3, 2022

Cincinnati, OH, US

Facility:  Main Campus

Nearest Major Market: Cincinnati

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