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Post Doc Fellow, Cancer Biology

Date: Feb 5, 2021

Location: Cincinnati, OH, US

Company: University of Cincinnati

Current UC employees must apply internally via SuccessFactors > http://bit.ly/UCEMPL

 

Job Overview

The University of Cincinnati, College of Medicine, Department of Cancer Biology is seeking a full-time Post Doctoral Fellow to work in the Dr. Jun-Lin Guan laboratory. 


 
The Postdoctoral position is available to pursue basic and translational cancer research in Dr. Jun-Lin Guan's laboratory at University of Cincinnati College of Medicine. Research in Dr. Guan's laboratory aims to understand the fundamental principles of cell signaling in the regulation of basic cellular functions in normal cell and developmental processes and to determine how the disruption of normal signaling pathways lead to diseases such as cancer. Current studies include the analysis of FIP200 and other autophagy genes in breast cancer and neural stem cells, mTORC1 signaling in vascular and other tumors and its cross-talk with autophagy. We use a variety of genetically engineered mouse models combined with molecular, cellular and functional genomic approaches to gain mechanistic insights of critical molecules and their complex signaling networks in vivo.


 
 Please see Cancer Res. 2020 (https://cancerres.aacrjournals.org/content/early/2020/06/24/0008-5472.CAN-20-0519), Elife 2020 (https://doi.org/10.7554/eLife.58810), Nature Metabolism 2019 (https://www.nature.com/articles/s42255-019-0137-5), JCB 2017 (https://rupress.org/jcb/article/216/8/2581/39169/Autophagy-gene-FIP200-in-neural-progenitors-non), Genes Dev. 2016 (http://genesdev.cshlp.org/content/30/7/856.full), Cancer Res. 2016 (https://cancerres.aacrjournals.org/content/76/11/3397), Cancer Cell 2015 (http://dx.doi.org/10.1016/j.ccell.2015.10.004), and Cell Press Sneak Peek 2020 (https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3661948) for a selection of recent studies from our laboratory.
 


The Department of Cancer Biology in the University of Cincinnati College of Medicine provides a dynamic, interactive and supportive environment. We are a well-established laboratory with extensive experiences and contributions in cancer research as well as a strong training record for postdocs over nearly 3 decades at Cornell University, University of Michigan, and University of Cincinnati.
 


Please see https://med.uc.edu/depart/cancer-biology/about/chair about Dr. Guan and visit https://med.uc.edu/depart/cancer-biology/labs/guan-laboratory for more information on our laboratory and the outstanding research training environments for postdoctoral fellows and associates.


 
We are interested in recruiting self-motivated, Ph.D. or M.D./Ph.D. graduates with the drive to succeed and the desire to be competitive at the highest level. Candidates with a strong background in cell and molecular biology, cancer research, vascular biology and/or immunology are encouraged to apply. Experience in autophagy, cell signaling, vesicle trafficking, single-cell transcriptional and genomic analysis, stem cells, and mouse models of cancer or other diseases will be a plus.

Essential Functions

  • Conduct research experiments in a particular field within the pre-determined research scope and methodology.
  • Gather and analyze data and develop new ideas that promote current research.
  • Prepare data summaries, reports, manuscripts and presentations of research results.
  • Participate/assist in manuscript writing for publication in scientific journals and/or presentation; may assist in grant writing.
  • Keep informed of developments in field to maintain and enhance professional expertise.
  • Lab maintenance, including equipment maintenance and ordering of supplies, as needed.
  • May teach techniques to others, train, and mentor junior research staff.
  • Engage in appropriate training and professional development opportunities.
  • Play an active role in seeking career and research advice, both from the faculty supervisor and from other faculty members as well.
  • Perform related duties based on departmental need. This job description can be changed at any time.

Required Education

Ph.D. or M.D./Ph.D

Required Experience

  • Experience in cell and molecular biology, cancer research, vascular biology and/or immunology.
  • Experience in autophagy, cell signaling, vesicle trafficking, single-cell transcriptional and genomic analysis, stem cells, and mouse models of cancer or other diseases will be a plus.

Application Process

  • Create an 'Applicant Profile' at https://jobs.uc.edu and upload your CV/Resume and contact information of three (3) references.  Please upload, under the 'Additional Documents' section of the application, a short statement of research interest.
  • For additional information concerning this position you may contact Jun-Lin Guan, Ph.D. Professor and Chair, Department of Cancer Biology, University of Cincinnati College of Medicine, Vontz Center for Molecular Studies Rm 3324, 3125 Eden Avenue Cincinnati, OH  45267-0521. E-mail: guanjl@uc.edu. Tel/Fax: (513) 558-0114/(513) 558-1190.

 

The University of Cincinnati, as a multi-national and culturally diverse university, is committed to providing an inclusive, equitable and diverse place of learning and employment. As part of a complete job application you will be asked to include a Contribution to Diversity and Inclusion statement.

 

As a UC employee, and an employee of an Ohio public institution, if hired you will not contribute to the federal Social Security system, other than contributions to Medicare. Instead, UC employees have the option to contribute to a state retirement plan (OPERS, STRS) or an alternative retirement plan (ARP).

 

The University of Cincinnati is an Affirmative Action / Equal Opportunity Employer / Minority / Female / Disability / Veteran.

 

REQ: 60541 

SF:LJN (OMJ) SF:RM SF:HEJ SF:INS SF:HERC SF:DIV


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